Antioxidant Activity of White Turi Leaves Extract (Sesbania grandiflora (L.) Pers) on Heart Organ CKMB and Cholesterol Parameters in Induced Rats Toxic Doses of Paracetamol
Aktivitas Antioksidan Ekstrak Daun Turi Putih (Sesbania grandiflora (L.) Pers) terhadap Organ Jantung Parameter CKMB dan Kolesterol pada Tikus yang Diinduksi Paracetamol Dosis Toksik
DOI:
https://doi.org/10.21070/ups.7093Keywords:
Antioxidant, white turi leaf, Sesbania grandiflora (L.) Pers, hepar, paracetamol, MDA (malondialdehyde), Cholesterol, CK-MBAbstract
White Turi leaves (Sesbania grandiflora (L) Pers.) are a plant that has the potential to be a natural antioxidant. This study aims to determine the antioxidant activity of white turi leaf extract on the heart of male white rats (Rattus novergicus) induced with a toxic dose of paracetamol. This study is a laboratory experimental study with a randomized controlled design and a pre-postt control only group design research pattern. This study used 35 male Wistar rats divided into 7 treatment groups. Measurement of antioxidant activity was carried out by measuring MDA levels, measuring kidney function was carried out by measuring cholesterol and CK-MB levels, and macroscopic observation of the kidneys.
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