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Risk Factor of The Incidence of Hyperemesis Gravidarum: A Population-based Case-control Study


Faktor Resiko Kejadian Hiperemesis Gravidarum: Studi Kasus-kontrol Berbasis Populasi

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DOI:

https://doi.org/10.21070/ups.1265

Keywords:

hyperemesis gravidarum, pregnancy, risk factor

Abstract

Hyperemesis Gravidarum is severe and excessive nausea and vomiting, starting at 4 and 6 weeks of gestation and peaking at 8-12 weeks of pregnancy, and usually subsiding by 20 weeks of gestation.  To recognize the risk factors for the incidence of hyperemesis gravidarum to detect early and reduce the consequences of hyperemesis gravidarum. This type of research is an analytical observational study with the research design of the Case Control method with a sample size of240.  This study uses secondary data, the instrument used is a data collection sheet with data sources coming from medical records. The results showed that risk factors have an association with the incidence of hyperemesis gravidarum, namely the age of pregnant women (p=0.014<0.05,OR0.38,).Parity (p=0.008,OR=2.14,).Gestational age(p=0.000,OR=49.63).Education(p=0.188,OR=0.500).Maternal occupation(p=0.002,OR=2.34).Maternal pregnancy spacing (p=0.004,OR=2.17),anemia in pregnancy(p=0.032<0.05,OR=0.422)and maternal status(p=0.004,OR=2.22). Almost all risk factors studied had a relationship Maternal age, parity,gestational age,maternal employment,pregnancy distance,anemia,and BMI status are risk factors for hyperemesis gravidarum. 

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References

Nurarif AH, Kusuma H. Asuhan keperawatan praktis berdasarkan penerapan diagnosa Nanda, NIC, NOC dalam berbagai kasus. Edisi .Revisi,. Rahil NH, editor. Jogjakarta: Media Action Publishing; 2016. 435 p.

Nithiyasri P, Monika S, Leelashree T, Lokesh G, Priya DJ. Prevalence and risk factors of hyperemesis gravidarum: A retrospective study. Medico-Legal Update. 2020;20(2):132–5.

Topalahmetoğlu Y, Altay MM, Cırık DA, Tohma YA, Çolak E, Çoşkun B, et al. Depression and anxiety disorder in hyperemesis gravidarum: A prospective case-control study. Turkish Journal of Obstetrics and Gynecology. 2017;14(4):214–9.

Jenabi E, Fereidooni B. The association between maternal smoking and hyperemesis gravidarum: a meta-analysis. Journal of Maternal-Fetal and Neonatal Medicine. 2017;30(6):693–7.

Gabra A. Complications of Hyperemesis Gravidarum; A Disease of Both Mother and Fetus, Review Article. Critical Care Obstetrics and Gynecology. 2019;05(01):1–5.

Pan X, Chu R, Meng J, Wang Q, Zhang Y, Song K, et al. Simpson, M., DipRemedial Therapies, MHNA, Parsons, M., Greenwood, J. and Wade, K. (2001), Raspberry leaf in pregnancy: its safety and efficacy in labor. The Journal of Midwifery & Women Health, 46: 51-59. 2021;1–7.

Fiaschi L, Nelson-Piercy C, Tata LJ. Hospital admission for hyperemesis gravidarum: A nationwide study of occurrence, reoccurrence and risk factors among 8.2 million pregnancies. Human Reproduction. 2016 Aug 1;31(8):1675–84.

Nurmi M, Rautava P, Gissler M, Vahlberg T, Polo-Kantola P. Incidence and risk factors of hyperemesis gravidarum: A national register-based study in Finland, 2005-2017. Acta Obstetricia et Gynecologica Scandinavica. 2020 Aug 1;99(8):1003–13.

Kim HY, Cho GJ, Kim SY, Lee KM, Ahn KH, Han SW, et al. Pre-pregnancy risk factors for severe hyperemesis gravidarum: Korean population based cohort study. Life. 2021;11(1):1–8.

Beevi Z, Low WY, Hassan J. Impact of hypnosis intervention in alleviating psychological and physical symptoms during pregnancy. American Journal of Clinical Hypnosis. 2016;58(4):368–82.

Aminu MB, Alkali M, Audu BM, Abdulrazak T, Bathna D. Prevalence of hyperemesis gravidarum and associated risk factors among pregnant women in a tertiary health facility in Northeast, Nigeria. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2020 Aug 27;9(9):3557.

Mekonnen AG, Amogne FK, Worku Kassahun C. Risk Factors of Hyperemesis Gravidarum among Pregnant Women in Bale Zone Hospitals, Southeast Ethiopia: Unmatched Case-Control Study. Clinics in Mother and Child Health. 2018;15(3).

Sharp BR, Sharp KM, Patterson MDB, Dooley-Hash S. Treatment of nausea and vomiting in pregnancy: Factors associated with ED revisits. Western Journal of Emergency Medicine. 2016 Sep 1;17(5):585–90.

Mullin PM, Ching C, Schoenberg F, MacGibbon K, Romero R, Goodwin TM, et al. Risk factors, treatments, and outcomes associated with prolonged hyperemesis gravidarum. Journal of Maternal-Fetal and Neonatal Medicine. 2012 Jun;25(6):632–6.

Ioannidou P, Papanikolaou D, Mikos T, Mastorakos G, Goulis DG. Predictive factors of Hyperemesis Gravidarum: A systematic review. Vol. 238, European Journal of Obstetrics and Gynecology and Reproductive Biology. Elsevier Ireland Ltd; 2019. p. 178–87.

Roseboom TJ, Ravelli ACJ, Van Der Post JA, Painter RC. Maternal characteristics largely explain poor pregnancy outcomes after hyperemesis gravidarum. Journal of Obstetrics and Gynecology and Reproductive Biology. 2011;156(1):56–9.

Munisah M, Sukarsih RI, Rachmawati A, Mudlikah S. Faktor Tingkat Pendidikan, Usia, Paritas, Status Pekerjaan dan Riwayat Emesis Gravidarum Mempengaruhi Terjadinya Emesis Gravidarum Pada Ibu Hamil Trimester I. IJMT : Indonesian Journal of Midwifery Today.2022;2(1):45–53.Availablefrom: http://journal.umg.ac.id/index.php/ijmt/article/view/4006

Nurhasanah N, Aisyah S, Amalia R. Hubungan Jarak Kehamilan, Pekerjaan dan Paritas dengan Kejadian Hiperemesis Gravidarum Pada Ibu Hamil. Jurnal Ilmiah Universitas Batanghari Jambi. 2022;22(2):736.

Dictara AA, Angraini DI, Mayasari D, Karyus A. Hubungan Asupan Makan dengan Kejadian Kurang Energi Kronis ( KEK ) pada Ibu Hamil di Wilayah Kerja Puskesmas Sukaraja Kota Bandar Lampung. Major. 2020;9(2):1–6.

Aslan MM, Yeler MT, Blylk İ, Yuvacl HU, Cevrioǧlu AS, Özden S. Hematological Parameters to Predict the Severity of Hyperemesis Gravidarum and Ketonuria. Revista Brasileira de Ginecologia e Obstetricia. 2022 May 1;44(5):458–66.

Boelig RC. The dilemma of hyperemesis gravidarum: more answers, and more questions. Available from: https://doi.org/10.3945/ajcn.

Bolin M, Åkerud H, Cnattingius S, Stephansson O, Wikström AK. Hyperemesis gravidarum and risks of placental dysfunction disorders: A population-based cohort study. BJOG: An International Journal of Obstetrics and Gynaecology. 2013;120(5):541–7.

Nurmi M, Rautava P, Gissler M, Vahlberg T, Polo-Kantola P. Recurrence patterns of hyperemesis gravidarum. American Journal of Obstetrics and Gynecology. 2018 Nov 1;219(5):469.e1-469.e10.

Posted

2023-05-29