Obesity and Chronic Hypertension in Relation to the Incidence of Preeclampsia
Obesitas dan Hipertensi Kronik Dengan Kejadian Preeklampsia
DOI:
https://doi.org/10.21070/ups.12290Keywords:
preeclampsia, obesity, chronic hypertension, pregnancyAbstract
Preeclampsia is a major contributor to maternal morbidity and mortality and may be associated with several risk factors, particularly obesity and chronic hypertension. This study examined the relationship of obesity and chronic hypertension with preeclampsia The study used an observational analytic case control design and analyzed secondary data from medical records collected for January–December 2025. A total of 146 respondents, consisting of 73 cases and 73 controls, were selected using consecutive sampling. Obesity was classified as a body mass index (BMI) ≥27 kg/m², whereas chronic hypertension was identified based on a history of hypertension before pregnancy or prior to 20 weeks of gestation. Data were analyzed using the Chi-Square test. Obesity was significantly associated with preeclampsia (p=0.005; OR=3.018; 95% CI=1.451–6.276). Chronic hypertension was also significantly associated with preeclampsia (p<0.001; OR=57.054; 95% CI=12.957–251.226). In conclusion, obesity and chronic
hypertension were significantly associated with preeclampsia.
Downloads
References
Siswati, I. Ismawati, D. Meidia Puspitasari, L. Mafudiah, A. Roswita Kue, and R. Susanti, “Literatur Review: Hubungan MAP (Mean Arterial Pressure), ROT (Roll Over Test) dan IMT (Index Masa Tubuh) / BMI (Body Mass Indeks) dengan Kejadian Preeklampsia pada Ibu Hamil,” Prosiding Seminar Nasional dan Call for Paper Kebidanan Universitas Ngudi Waluyo, vol. 2, no. 1, pp. 34–46, 2023.
Cleveland Clinic, “Preeclampsia: Toxemia, Causes, Symptoms & Risk Factors,” Cleveland Clinic. Accessed: Jun. 11, 2025. [Online]. Available: https://my.clevelandclinic.org/health/diseases/17952-preeclampsia
World Health Organization, “Pre-eclampsia,” World Health Organization. Accessed: Jan. 14, 2026. [Online]. Available: https://www.who.int/news-room/fact-sheets/detail/pre-eclampsia
Kementerian Kesehatan Republik Indonesia, Profil Kesehatan Indonesia 2024. Jakarta: Kementerian Kesehatan Republik Indonesia, 2025.
H. Choi et al., “Impact of pre-pregnancy body mass index and gestational weight gain on the risk of maternal and infant pregnancy complications in Korean women,” International Journal of Obesity, vol. 46, no. 1, pp. 59–67, 2022, doi: 10.1038/s41366-021-00946-8.
H. Haslan and I. Trisutrisno, “Dampak Kejadian Preeklamsia dalam Kehamilan Terhadap Pertumbuhan Janin Intrauterine,” Jurnal Ilmiah Kesehatan Sandi Husada, vol. 11, no. 2, pp. 445–454, 2022, doi: 10.35816/jiskh.v11i2.810.
M. A. S. Pramesti, M. A. M. Wulandari, N. Yumna, and H. Santosa, “Hubungan Paritas, Riwayat Hipertensi, dan Indeks Massa Tubuh dengan Kejadian Preeklampsia,” Jurnal Sehat Indonesia, vol. 6, no. 2, pp. 431–442, 2024, doi: 10.59141/jsi.v6i02.95.
M. Hanifa and D. D. Cahyani, “Faktor-Faktor yang Berhubungan dengan Kejadian Preeklamsia pada Ibu Hamil: A Literature Review,” An Idea Nursing Journal, vol. 2, no. 1, pp. 41–53, 2023, doi: 10.53690/inj.v2i01.143.
L. E. Martanti, S. P. Sari, and I. Ariyanti, “Jarak Kehamilan dan Obesitas sebagai Faktor Risiko Preeklamsia pada Kehamilan,” Higeia Journal of Public Health Research and Development, vol. 8, no. 2, pp. 246–256, 2024, doi: 10.15294/higeia.v8i5.76450.
I. Gusti, N. Prema, D. Wisesa, R. Purbowati, and R. Arimbi, “Hubungan Antara Indeks Massa Tubuh Dengan Kejadian Preeklampsia Pada Ibu Hamil di RSIA Ibunda Lampung Timur Tahun 2022–2023,” Jurnal Sehat Indonesia, vol. 7, no. 2, pp. 1371–1378, 2025.
M. Angellia Shyama Putri, I. Kurniati, G. T. Putri, and E. Kurniawaty, “Tinjauan Pustaka: Pengaruh Hipertensi Kronis pada Ibu Hamil terhadap Kejadian Preeklampsia,” Medula, vol. 15, no. 1, pp. 118–121, 2025.
Anita, Aprina, and T. Astuti, “Faktor Usia, Paritas, Jarak Kehamilan, Obesitas dan Riwayat Hipertensi dengan Kejadian Terjadinya Preeklamsia Ibu Hamil di Kota Agung Kabupaten Tanggamus,” Malahayati Nursing Journal, vol. 7, no. 7, pp. 2767–2780, 2025, doi: https://doi.org/10.33024/mnj.v7i7.20894
E. Poniedziałek-Czajkowska, R. Mierzyński, and B. Leszczyńska-Gorzelak, “Preeclampsia and Obesity—The Preventive Role of Exercise,” International Journal of Environmental Research and Public Health, vol. 20, no. 2, pp. 1–39, 2023, doi: 10.3390/ijerph20021267.
F. Sari, N. Widiya Ningrum, and E. Yuandari, “Faktor-Faktor yang Berhubungan dengan Kejadian Preeklamsia pada Ibu Hamil di RSUD Pambalah Batung,” Health Research Journal of Indonesia (HRJI), vol. 1, no. 5, pp. 208–215, 2023.
M. Y. Abramova and M. I. Churnosov, “Modern concepts of etiology, pathogenesis and risk factors for preeclampsia,” Journal of Obstetrics and Women’s Diseases, vol. 70, no. 5, pp. 105–116, 2021, doi: 10.17816/JOWD77046.
A. Regita and Y. Nur Khayati, “Riwayat Preeklampsia, Usia dan Paritas Ibu Meningkatkan Resiko Preeklampsia, Studi Case Control di RSUD Gondosuwarno Ungaran,” Journal of Holistics and Health Sciences, vol. 6, no. 2, pp. 230–240, 2024, doi: 10.35473/jhhs.v6i2.483.
C. W. Ives, R. Sinkey, I. Rajapreyar, A. T. N. Tita, and S. Oparil, “Preeclampsia—Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review,” Journal of the American College of Cardiology, vol. 76, no. 14, pp. 1690–1702, 2020, doi: 10.1016/j.jacc.2020.08.014.
L. N. Tiara Putri, N. Harahap, and N. Handayani, “Faktor-Faktor yang Berhubungan dengan Kejadian Preeklampsia pada Ibu Hamil di Rumah Sakit Citra Medika Depok Tahun 2023,” Indonesian Journal of Midwifery Scientific, vol. 3, no. 2, pp. 35–45, 2024.
Y. Akasaki, “Angiogenic factors for early prediction of preeclampsia,” Hypertension Research, vol. 47, no. 10, pp. 2959–2960, 2024, doi: 10.1038/s41440-024-01846-w.
J. . Torres-Torres et al., “A Narrative Review on the Pathophysiology of Preeclampsia,” International Journal of Molecular Sciences, vol. 25, no. 14, pp. 1–24, 2024, doi: 10.3390/ijms25147569.
M. L. W. Kinshella et al., “Maternal nutritional risk factors for pre-eclampsia incidence: findings from a narrative scoping review,” Reproductive Health, vol. 19, no. 1, pp. 1–13, 2022, doi: 10.1186/s12978-022-01485-9.
W. Riskyna Harmawan, N. Fransisca Ngo, N. Hasanah, E. Sawitri, and A. Adi Saputra Ahmad, “Riwayat Penggunaan Kontrasepsi Hormonal, Riwayat Preeklampsia dan Hipertensi Kronik Berhubungan dengan Kejadian Preeklampsia,” Jurnal Medika: Karya Ilmiah Kesehatan, vol. 7, no. 1, pp. 1–8, 2022.
World Health Organization, WHO Recommendations on Antenatal Care for a Positive Pregnancy Experience. Geneva, Switzerland: World Health Organization, 2016. Accessed: Aug. 9, 2026. [Online]. Available: https://www.who.int/publications/i/item/9789241549912
World Health Organization, “Targets of Sustainable Development Goal 3,” World Health Organization. Accessed: Aug. 9, 2026. [Online]. Available: https://www.who.int/europe/about-us/our-work/sustainable-development-goals/targets-of-sustainable-development-goal-3
Downloads
Additional Files
Posted
Categories
License
Copyright (c) 2026 UMSIDA Preprints Server

This work is licensed under a Creative Commons Attribution 4.0 International License.
