Correlation of Erythrocyte Count and Hemoglobin Levels with Hemoglobin Electrophoresis in Thalasemia Patients
Korelasi Jumlah Eritrosit dan Kadar Hemoglobin dengan Hemoglobin Elektroforesis pada Pasien Thalasemia
DOI:
https://doi.org/10.21070/ups.11287Keywords:
thalassemia, hemoglobin levels, erythrocyte, hemoglobin electrophoresisAbstract
Thalassemia caused by a mutation in the globin gene that causes a decrease in the production of one of the globin chains. This study uses secondary data with a quantitative analysis research design with cross-sectional approach, which aims to determine the correlation between the number of erythrocytes and hemoglobin levels with hemoglobin electrophoresis in thalassemia patients at Dr. Saiful Anwar Regional General Hospital, East Java Province, as many as 50 samples from October 2023 to May 2026. Based on the results of the Spearman correlation analysis, it shows a significant correlation between total Hb levels and HbA (r=0.290), (p=0.020). Hb levels with HbA2 do not show a correlation (r=-0.056), (p=0.351). The number of erythrocytes doesn't show a correlation with Hb A (r=0.032), (p=0.414), but shows positive correlation with Hb A2 (r=0.261), (p=0.034). So the total Hb level is related to HbA, while the number of erythrocytes is related to HbA2.
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