Preprint has been published in a journal as an article
Preprint / Version 1

The Effect of Alcohol Consumption in Adolescents on Serum Glutamic Oxaloacetic Transaminase (SGOT) And Serum Glutamic Pyruvic Transaminase (SGPT) Levels

Pengaruh Konsumsi Alkohol pada Remaja terhadap Kadar Serum Glutamic Oxaloacetic Transaminase (SGOT) dan Serum Glutamic Pyruvic Transaminase (SGPT)

##article.authors##

DOI:

https://doi.org/10.21070/ups.8477

Keywords:

Alcohol Consumption, SGOT, SGPT, Adolescents

Abstract

Alcohol is a psychoactive substance with addictive properties due to its selective function, especially on the brain, changing behavior, emotions, cognition, views, and consciousness. Addiction or dependence on alcohol is known as the addictive nature of alcohol. Serum GlutamicOxaloacetic Transaminase (SGOT) is an enzyme whose presence and levels in the blood are used as markers of liver dysfunction.  Using an experimental laboratory research design with a cross-sectional approach, this study involved 30 adolescent respondents from the Balongbendo and Tulangan areas who were alcohol consumers.  The results of data analysis using the Independent samples T-Test showed that there was no significant difference (p = 0.087) in SGOT levels, but there was a significant difference (p = 0.000) in SGPT levels in adolescents consuming alcohol for 1-3 years and >3-5 years. These findings indicate that alcohol consumption can affect liver function, especially in increasing SGPT levels.organs.

Downloads

Download data is not yet available.

References

Kemenkes RI, “Intoksikasi Alkohol.” [Online]. Available: https://yankes.kemkes.go.id/view_artikel/1149/intoksikasi-alkohol

Shinta Fatmawati Yeni Avidhatul Husnah Previta Zeizar Rahmawati. Pemeriksaan Dampak Mengkonsumsi Minuman Beralkohol Terhadap Kadar Enzim Aspartat Aminotransferase (AST) dan Alanine Aminotransferase (ALT). jurnal labortorium medis.vol 06 No 02,pp 2685-8495, 2024.

BKKBN, BPS, andK.RI, LaporanSDKI2017KesehatanReproduksiRemaja.2018.[Online]. Available: https://archive.org/details/LaporanSDKI2017Remaja.

Dewi, “Kadar Serum Glutamate Piruvat Transaminase Pecandu Minuman Keras Di Banjar Ambengan Desa Sayan Ubud GianyarIGATari Diva Pradnya Dewi 1, Nyoman Mastra 2,IWayan Merta 3,”Meditory, vol. 4, no. 3, pp. 82–93, 2016.

R. Sulistiyowati and F. Aziz Nurzhorif, “Hubungan Lama Konsumsi Minuman Berakohol Dengan Kadar SGOT dan SGPT di Desa Kemojing Kecamatan Binangun Kabupaten Cilacap,” Cendekia utama, vol. 11,no. 3, 2022.

D. Conreng, B. J. Waleleng, and S. Palar, “Hubungan Konsumsi Alkohol Dengan Gangguan Fungsi Hati Pada Subjek Pria Dewasa Muda Di Kelurahan Tateli Dan Teling Atas Manado,” e-CliniC, vol. 2, no. 2, pp. 2–5, 2014, doi: 10.35790/ecl.2.2.2014.5026.

T. R. Puji Lestari, “Menyoal Pengaturan Konsumsi Minuman Beralkohol di Indonesia,” Aspir. J. Masal. Sos., vol. 7, no. 2, pp. 127–141, 2019, doi: 10.46807/aspirasi.v7i2.1285.

V. Y. Lomanorek and Y. A. Assa, “Gambaran Kadar Serum Serum Glutamic Oxaloacetic Transaminase (Sgot) Pada Perokok Aktif Usia > 40 Tahun,” J. e-Biomedik, vol. 4, no. 1, 2016, doi: 10.35790/ebm.4.1.2016.11046.

M.Sidi,“Gambaran Kadar SGPT (Serum glutamic pyruvic transaminase) Pada Perokok Aktif,”pp.12–13,

A. Farihatun, E. S. N. Janah, D. K. Yulianti, M. Edhiatmi, and D. Yayuningsih, “SGPT Levels (Serum Glutamic Pyruvat Transminase) On Pil KB Contraception Acceptors,” J. Kesehat., vol. 7, pp. 39–43, 2020.

R. Sulistiyowati and F. Aziz Nurzhorif, “Hubungan Lama Konsumsi Minuman Berakohol Dengan Kadar SGOT dan SGPT di Desa Kemojing Kecamatan Binangun Kabupaten Cilacap,” Cendekia utama, vol. 11,no. 3, 2022.

IEsther, R Susanti,Ayuniastuti, “Efektifitas Pati Gembili ( Dioscorea esculenta) Terhadap Kadar ALT (Alanine Aminotransferase)dan AST(Aspartate Aminotransferase) Pada Tikus Hiperkolesterolemia” jil 9,2021,https://proceeding.unnes.ac.id/semnasbiologi/article/view/781

L. zhung, p and Z. L, “Association between alkohol consumption and liver enzyme levels: A Systematic review meta-anlysis,” J. Hepatol., vol. 78, no. 4, pp. 743–755, 2023, doi: 10.1016/j.jhep.2023.01.012.

R. S. Panjaitan, “Pengaruh Sistem Kerja Shift Terhadap Gambaran Enzim Fungsi Hati (SGOT dan SGPT) pada Karyawan Pabrik Peleburan Aluminium PT Inalum (Persero ) Kuala Anjung Tahun 2017,” pp. 1–71, 2018.

Yoganadh T,S. Mayilsamy,R. Shankar, “Comparison OfHematological ParametersBetween Alcoholics and Non-Alcoholics” Int J Res MedSci.,vol. 11 no. 5041-5047,201

Aravind G. N., Abhilash K., Syed Umar Farooq, “A Study of alanine aminotransferase –aspartate aminotransferase as a marker of advance alcoholic liver disease ,Internasional journal of advances in medicine , vol.07 no.4

Posted

2025-07-11