Correlation Hemoglobin and Hematocrit Levels with Total Iron Binding Capacity (TIBC) Levels in Chronic Kidney Disease Patients
Korelasi Kadar Hemoglobin dan Hematokrit dengan Kadar Total Iron Binding Capacity (TIBC) pada Pasien Gagal Ginjal Kronik
DOI:
https://doi.org/10.21070/ups.8361Keywords:
Chronic Kidney Disease, Hemoglobin, Hematocrit, TIBCAbstract
Chronic Kidney Failure (CKD) is a condition where the kidneys are structurally and functionally damaged characterized by a decrease in Glomerular Filtration Rate (GFR) reaching ≤ 60 ml/min/1.73m2 for more than three months. About 80 - 90% of patients with GGK experience anemia. The purpose of this study was to determine the correlation of hemoglobin and hematocrit levels with Total Iron Binding Capacity (TIBC) levels in patients with chronic renal failure. This study was conducted at the East Java Province Hajj Hospital in March 2025. The study used secondary data as many as 55 respondents of CKD undergoing hemodialysis. The results of the correlation test can be concluded that there is no correlation between hemoglobin levels with TIBC (r = 0.134; p = 0.154), and hematocrit with TIBC levels (r = 0.172; p = 0.066) in Chronic Renal Failure patients undergoing Hemodialysis at Hajj Hospital, East Java province.
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M. H. Falah, T. Setyawati, R. M. Walanda, and I. R. Putrie, “Hubungan Kadar Kreatinin dengan Hemoglobin pada Pasien Gagal Ginjal Kronik (GGK) di RSUD Undata Provinsi Sulawesi Tengah Tahun 2022,” Medika Tadulako, vol. 9, no. 1, pp. 40–46, 2024, [Online]. Available: https://jurnal.fk.untad.ac.id/index.php/mtj/article/view/1255/572
N. Z. Aditama, H. Kusumajaya, and N. Fitri, “Faktor-Faktor yang Berhubungan dengan Kualitas Tidur Pasien Gagal Ginjal Kronis,” Jurnal Penelitian Perawat Profesional, vol. 6, no. 1, pp. 109–120, 2023, [Online]. Available: https://jurnal.globalhealthsciencegroup.com/index.php/JPPP/article/view/1919/1579
Y. W. Ngara, Y. Rosdiana, and W. Rahayu, “Harga Diri Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik (GGK) Yang Menjalani Hemodialisa Pada Masa Pandemi Covid-19,” Care : Jurnal Ilmiah Ilmu Kesehatan, vol. 10, no. 2, pp. 304–314, 2022, doi: 10.33366/jc.v10i2.3627.
A. A. Alfonso, A. E. Mongan, and M. F. Memah, “Gambaran Kadar Kreatinin Serum pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis,” Jurnal e-Biomedik, vol. 4, no. 2, pp. 2–7, Jul. 2016, [Online]. Available: https://ejournal.unsrat.ac.id/v3/index.php/ebiomedik/article/view/10862/10450
National Institute of Diabetes and Digestive and Kidney Deases, “Hemodialisis,” niddk.nih.gov. [Online]. Available: https://www.niddk.nih.gov/health-information/kidney-disease/kidney-failure/hemodialysis
N. W. Heriansyah, Aji Humaedi, “Gambaran Ureum Dan Kreatinin Pada Pasien Gagal Ginjal Kronis Di Rsud Karawang,” Binawan Student Journal, vol. 01, no. 01, pp. 8–14, 2019.
W. Fatresia, M. Wulandari, R. Alfarisi, and Hidayat, “Perbedaan Jumlah Eritrosit Sebelum dan Sesudah Hemodialisa Pada Pasien Laki-laki Dengan Gagal Ginjal Kronik,” Jurnal Penelitian Perawat Profesional, vol. 6, no. 6, pp. 2373–2382, 2024.
W. Yuniarti, “Anemia pada Pasien Gagal Ginjal Kronik Anemia in Chronic Kidney Disease Patients,” Journal Health And Science ; Gorontalo Journal Health & Science Community, vol. 5, no. 2, pp. 341–347, 2021.
KEMENKES, “Keputusan Menteri Kesehatan RI Tentang Pedomal Tata Laksana Gagal Ginjal Kronik,” 2023.
A. S. Elsayed and A. E. Azab, “Correlation between chronic kidney diseases and hematolgical data in sabratha hospital in libya,” Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 2, pp. 291–296, 2017, doi: 10.22159/AJPCR.2017.V10I2.15595.
L. V. Thang et al., “Serum total iron-binding capacity and iron status in patients with non-dialysis-dependent chronic kidney disease: A cross-sectional study in Vietnam,” Asia Pacific journal of clinical nutrition, vol. 29, no. 1, pp. 48–54, 2020, doi: 10.6133/apjcn.202003_29(1).0007.
L. Ekowati, “Korelasi Antara Kadar Hemoglobin Dengan Total Iron Binding Capacity (TIBC) Pada Penderita Penyakit Ginjal Kronik (PGK) Derajat V Yang Menjalani Hemodialisis Di Rs Toeloengredjo Pare Kediri,” Jurnal Insan Cendekia, vol. 10, no. 2, pp. 99–105, 2023, doi: 10.35874/jic.v10i2.1227.
N. Wayan, A. M. Dewi, L. Gede, S. Yenny, and P. N. Cahyawati, “Hubungan Kadar Kreatinin dan Ureum dengan Derajat Anemia pada Pasien Penyakit Ginjal Kronik di RSUD Sanjiwani Gianyar,” AMJ (Aesculapius Medical Journal), vol. 3, no. 1, pp. 74–80, 2023, [Online]. Available: https://www.ejournal.warmadewa.ac.id/index.php/amj/article/view/5426
M. P. Lumbantobing, “Gambaran Kadar Hemoglobin dan Kadar Kreatinin pada Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis di RSUD Tarutung,” Jurnal Kedokteran Meditek, vol. 28, no. 3, pp. 264–268, 2022, doi: 10.36452/jkdoktmeditek.v28i3.2297.
F. Nuroini and W. Wijayanto, “Gambaran Kadar Ureum dan Kreatinin pada Pasien Gagal Ginjal Kronis di RSU Wirdadi Husada,” Jambura Journal of Health Sciences and Research, vol. 4, no. 2, pp. 538–545, 2022, doi: 10.35971/jjhsr.v4i2.13199.
D. Astuti and U. Kulsum, “Pola Menstruasi dengan Terjadinya Anemia pada Remaja Putri,” Jurnal Ilmu Keperawatan dan Kebidanan, vol. 11, no. 2, pp. 314–327, 2020, doi: 10.26751/jikk.v12i1.920.
A. Cases et al., “Anemia of chronic kidney disease: Protocol of study, management and referral to Nephrology,” Nefrología (English Edition), vol. 38, no. 1, pp. 8–12, 2018, doi: 10.1016/j.nefroe.2018.01.007.
B. J. Silaban, C. Sugeng, and B. J. Waleleng, “Gambaran status besi pada pasien penyakit ginjal kronik stadium 5 dengan anemia yang menjalani hemodialisis reguler,” Jurnal e-Clinic, vol. 4, no. 2, 2016, doi: 10.35790/ecl.4.2.2016.14372.
P. R. Devi and Y. W. Arif, “Kadar Total Iron Binding Capacity (TIBC) Pada Pasien Gagal Ginjal Kronis,” Kesehatan Aisyiyah, vol. 01, 2020, [Online]. Available: https://digilib.unisayogya.ac.id/5498/1/RIKA PUSPITA DEVI_1611304047_TLM_NASPUB - Rika Puspita Devi.pdf
Iron Disorders Institute, “Anemia Of Chronic Disease.” [Online]. Available: https://irondisorders.org/anemia-of-chronic-disease-2/#:~:text=In adults%2C anemia of chronic,an autoimmune disease is present.
N. F. Ulya, G. Kusdinar, and K. Santoso, “The correlation between creatinine serum with total iron binding capacity (TIBC) on patients with sufferers chronic renal disease in Gambiran regional public hospital Kediri city,” Medical Laboratory Analysis and Sciences Journal, vol. 1, no. 1, pp. 19–24, 2019, doi: 10.35584/melysa.v1i1.18.
Z. Arifin and B. R. Fatmawati, “Anemia Pada Pasien dengan Gagal Ginjal Kronik yang Menjalani Hemodialisa,” Jurnal Prima, vol. 9, no. 2, pp. 1–7, 2023.
S. Helmyati, F. C. Hasanah, F. Putri, T. Sundjaya, and C. Dilantika, “Biochemistry Indicators for the Identification of Iron Deficiency Anemia in Indonesia: A Literature Review,” Amerta Nutrition, vol. 7, no. 3, pp. 62–70, 2023, doi: 10.20473/amnt.v7i3SP.2023.62-70.
W. Rahmatullah, R. B. Labito, R. Aini, R. Azimata, and R. Handayani, “The Differences Of Edta And Heparin Anticoagulans On Hematocrit Value,” Jurnal Kesehatan Saintika Meditory, vol. 6, no. 1, pp. 331–341, 2023.
D. Eka Safitri, E. D. Woelansari, and Suhariyadi, “Relationship of Red Cell Distribution Width (RDW) To the Results Total Iron Binding Capacity (TIBC) In Chronic Kidney Failure Patients with Anemia,” Medicra (Journal of Medical Laboratory Science/Technology), vol. 5, no. 2, pp. 109–114, 2022, doi: 10.21070/medicra.v5i2.1648.
A. Faruqi and M. Zubair, Iron-Binding Capacity - StatPearls - NCBI Bookshelf (1). NCBI, 2024. [Online]. Available: https://www.ncbi.nlm.nih.gov/books/NBK559119/#__NBK559119_dtls__
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