Effect of Red Ginger Extract (Zingiber officinale roxb. var. rubrum) and Coriander Seeds (Coriandrum sativum L.) on MCV, MCH, and MCHC Values in Hyperlipidemia Conditions
Pengaruh Ekstrak Jahe Merah (Zingiber officinale roxb. var. rubrum) dan Biji Ketumbar (Coriandrum sativum L.) Terhadap Nilai MCV, MCH, dan MCHC Pada Kondisi Hiperlipidemia
DOI:
https://doi.org/10.21070/ups.7953Keywords:
Red Ginger Rhizome, Coriander Seed, MCV, MCH, MCHCAbstract
Hyperlipidemia is a metabolic disorder characterized by increased lipoproteins in the blood. Red ginger (Zingiber officanale roxb. var. rubrum) contains flavonoids, iron, and gingerol that help reduce cholesterol levels. Coriander seeds (Coriandrum sativum L.) contain flavonoids, iron, tannins, and saponins that are also beneficial for lowering cholesterol. Red ginger and coriander seeds were obtained from Porong Market, Sidoarjo. This study aims to determine the effect of red ginger and coriander seed extract on MCV, MCH, and MCHC values in hyperlipidemia. This laboratory experimental study used Pretest-Posttest Control Only Group design with 4 groups (control, red ginger extract 875 mg/kg bw, coriander seed extract 900 mg/kg bw, and 1:1 combination) involving 16 male white rats of Wistar strain. Cholesterol measurement using POCT method and MCV, MCH, MCHC values using Hematology Analyzer. The results showed a significant effect on MCV and MCH values, but not significant on MCHC.
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